Rabbits infected with CB demonstrated (1) higher lung weights in comparison to RM (P ≤ 0.05), RO and MC (P ≤ 0.001), (2) pulmonary infarcts in comparison to RO and MC (P ≤ 0.001), (3) tissue fungal burden (CFU/g) vs. microsporus (RM), and Mucor circinelloides (MC) in experimental invasive pulmonary mucormycosis in persistently neutropenic rabbits in relation to the fungi in vitro sporangiospore germination rate and hyphal metabolic activity. bertholletiae (CB), Rhizopus oryzae (RO), R. Therefore, we studied the relative virulence of C. Based upon our earlier epidemiological studies, we hypothesized that Cunninghamella bertholletiae would demonstrate increased virulence. However, little is known about the relation between different species of Mucorales and their virulence in invasive pulmonary mucormycosis. Members of the order Mucorales are emerging invasive molds that cause infections in immunocompromised patients.
0 Comments
Leave a Reply. |